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Meghan Garcia-Webb, MD, of Weight Medicine MD starts off by reminding readers that results can vary by person: The pace of weight loss depends on a variety of factors, including how well a patient is tolerating the medication, their pre-existing conditions, and medications they are on, she explains

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Consequently, tissue-level outcomes may depend not only on receptor activation but also on the availability of metabolic substrates required to sustain bioenergetic and redox balance under conditions of reduced nutrient inflow